On February 16, 2024, the Journal of Bone and Mineral Research (a peer-reviewed journal) posted the accepted manuscript "MMP-9 deficiency confers resilience in fibrodysplasia ossificans progressiva in a man and mice." Once you've clicked the link above, click the PDF icon to access the full manuscript.
A brief lay summary is available on page eight of the manuscript. We are grateful to patient-R and the researchers who have spent many years studying patient-R's extreme lack of heterotopic ossification (HO) and nearly normal mobility.
Corresponding Author: Frederick S. Kaplan, MD
Additional Authors:
Vitali Lounev, PhD
Jay C. Groppe, PhD
Niambi Brewer, PhD
Kelly L. Wentworth, MD
Victoria Smith, PhD
Meiqi Xu, BS
Lutz Schomburg, PhD
Pankaj Bhargava, MD
Mona Al Mukaddam, MD
Edward C. Hsiao, MD, PhD
Eileen M. Shore, PhD
Robert J. Pignolo MD, PhD
Thank you to the Journal of Bone & Mineral Research and Oxford University Press for making this manuscript "Free to Read," an important service to the FOP community.