How is the extra bone in FOP different from normal bone?


The extra bone in FOP forms by a progressive transformation of soft tissue into cartilage and bone. This is the same process by which bone regenerates (heals) after a fracture (break) occurs and is nearly identical to the process by which bone forms normally in an embryo. The abnormality in FOP occurs not in the manner of bone formation but rather in its timing and location.

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